EP0368253A2
Expired / Lapsed
EP
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Delivery system for pharmaceutical or therapeutic actives
Assignee: Union Carbide Chemicals and Plastics Technology LLC
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Filing: 1989-11-07
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Granted: —
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Expires: 2009-11-07
Abstract
Abstract Delivery systems containing at least one aminopolysaccharide derivative are provided for the delivery of pharmaceutical or therapeutic actives to a desired topical or mucous membrane site in a subject, and wherein upon delivery, the systems provides a biocompatible, substantive, gas permeable, film from which actives are available at the designated site.
Inventors
- 👤 Emmett Malone Partain, Iii
- 👤 Lewis Ii Brode
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 18:50
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K8/00; A61K8/18; A61K8/72; A61K8/73; A61K8/736; A61K47/00; A61K47/30; A61K47/36; A61K9/0012; A61K9/0014; A61K9/7015; A61L; A61L26/00; A61L26/0009; A61L26/0023; A61L26/0061; A61L26/0076; A61Q; A61Q17/00; A61Q17/04; A61Q19/00; B; B01; B01D; B01D71/00; B01D71/06; B01D71/08; C; C08; C08B; C08B37/00; C08B37/0006; C08B37/0024; C08B37/0027; C08B37/003; C08L; C08L5/00; C08L5/08; A61K2800/00; A61K2800/40; A61K2800/54; A61K2800/542; A61K2800/5426; A61Q7/00; Y; Y10; Y10S; Y10S261/00; Y10S261/88; Y10S424/00; Y10S424/15
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
51 words
A biocompatible, substantive, film-forming delivery system for the delivery of pharmaceutical or therapeutic actives to a desired topical site of a subject, said system comprising from about 0.01 to about 99.99 weight percent of the total system of at least one aminopolysaccharide selected from: (1) chitosonium polymers, and (2 )chitosan derivatives.
Claim 2
Dependent Claim
51 words
A biocompatible, substantive, film-forming delivery system for the delivery of pharmaceutical or therapeutic actives to a desired topical site of a subject, said system comprising from about 0.01 to about 99.99 weight percent of the total system of at least one aminopolysaccharide selected from: (1) chitosonium polymers, and (2 )chitosan derivatives.
Claim 3
Dependent Claim
15 words
The delivery system of claim 1 wherein said chitosan derivative is a covalent chitosan derivative.
Claim 4
Dependent Claim
30 words
The delivery system of claim 1 wherein said chitosan derivative is selected from chitosonium pyrrolidone carboxylate, chitosonium niacinate, chitosonium itaconate, chitosonium salicylate, chitosonium lactate and chitosonium glycolate and combinations thereof.
Claim 5
Dependent Claim
19 words
The delivery system of anyone of claims 1 to 3, wherein said chitosan derivative is blended with hyaluronic acid.
Claim 6
Dependent Claim
16 words
The delivery system of anyone of claims 1 to 4, which contains a pharmaceutically acceptable diluent.
Claim 7
Dependent Claim
36 words
The composition of anyone of claims 1 to 5, which is in the form of a film, a gel, a patch, an aerosol, a suppository, a fibre, a rod, microspheres or a hemostatic device or solution.
Claim 8
Dependent Claim
23 words
The composition of anyone of claims 1 to 6 which is a device selected from a pad, sponge and suture, particularly a suture.
Claim 9
Independent Claim
74 words
A method for the preparation of a delivery system for use in the administration of pharmaceutical and therapeutic actives to a topical or mucosa site of a subject, said delivery system comprising: (a) at least one pharmaceutically or therapeutically active component, (b) at least one aminopolysaccharide selected from: (1) chitosonium polymers and (2) chitosan derivatives; which method comprises blending at least one pharmaceutically or therapeutically active component with said aminopolysaccharide and optionally a diluent.
Claim 10
Independent Claim
74 words
A method for the preparation of a delivery system for use in the administration of pharmaceutical and therapeutic actives to a topical or mucosa site of a subject, said delivery system comprising: (a) at least one pharmaceutically or therapeutically active component, (b) at least one aminopolysaccharide selected from: (1) chitosonium polymers and (2) chitosan derivatives; which method comprises blending at least one pharmaceutically or therapeutically active component with said aminopolysaccharide and optionally a diluent.
Claim 11
Dependent Claim
26 words
The method of claim 8 wherein said aminopolysaccharide is dissolved in a solvent before blending and/or said active component is dissolved in a solvent before blending.
Claim 12
Independent Claim
42 words
A method for the topical administration of a pharmaceutical or therapeutic active to a subject, which comprises administering to said subject at a designated site a pharmaceutically or therapeutically effective amount of the delivery system of anyone of claims 1 to 7.
References Cited (Backward Citations)
No citation records indexed.
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