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EP0299381A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Membrane-type artificial lung and method of using it

Assignee: DIC Corp
•
Filing: 1988-07-08
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Granted: —
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Expires: 2008-07-08
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Abstract

Abstract To perform exchange of gases between blood and a gas through a membrane, blood is passed over one side of the membrane and oxygen or an oxygen-containing gas over the other side, said membrane being a hollow fiber membrane which is composed mainly of a polyolefin, has an inside dia­meter of 10 to 500 micrometers, a thickness of 5 to 100 micrometers, a porosity of 7 to 50 % and an oxygen flux, Q(O₂), of at least 1 x 10⁻⁶ [cm³ (STP)/(cm².sec.cmHg)] and is substantially impermeable to ethanol.

Inventors

  • 👤 Takanori Anazawa
  • 👤 Kazutaka Murata
  • 👤 Hiroyuki Akasu
  • 👤 Rishichi Mimura

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-22 22:53
CPC Classifications
B; B01; B01D; B01D67/00; B01D67/0002; B01D67/0023; B01D67/0025; B01F; B01F25/00; B01F25/30; B01F25/31; B01F25/313; B01D69/00; B01D69/02; B01D69/08; B01D71/00; B01D71/06; B01D71/26; B01D71/261; B01D71/262; B01F23/00; B01F23/20; B01F23/23; B01F23/231; B01F23/23105; B01F23/2312; B01F23/23123; B01F23/23124; A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1698; B01D2325/00; B01D2325/20

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 93 words
A membrane-type artificial lung adapted to perform exchange of gases between blood and a gas through a membrane by passing blood over one side of the membrane and oxygen or an oxygen-containing gas over the other side, said membrane being a hollow fiber membrane which is composed mainly of a polyolefin, has an inside dia­meter of 10 to 500 micrometers, a thickness of 5 to 100 micrometers, a porosity of 7 to 50 % and an oxygen flux, Q(O₂), of at least 1 x 10⁻⁶ [cm³ (STP)/(cm².sec.cmHg)] and is substantially impermeable to ethanol.
Claim 2
Dependent Claim 93 words
A membrane-type artificial lung adapted to perform exchange of gases between blood and a gas through a membrane by passing blood over one side of the membrane and oxygen or an oxygen-containing gas over the other side, said membrane being a hollow fiber membrane which is composed mainly of a polyolefin, has an inside dia­meter of 10 to 500 micrometers, a thickness of 5 to 100 micrometers, a porosity of 7 to 50 % and an oxygen flux, Q(O₂), of at least 1 x 10⁻⁶ [cm³ (STP)/(cm².sec.cmHg)] and is substantially impermeable to ethanol.
Claim 3
Dependent Claim 13 words
The membrane-type artificial lung of claim 1 in which the polyolefin is poly(4-methylpentene-1).
Claim 4
Dependent Claim 29 words
The membrane-type artificial lung of claim 1 in which the hollow fiber membrane had an oxygen flux, Q(O₂), at 25 °C of at least 7 x 10⁻⁶ cm³ (STP)/­(cm².sec.cmHg).
Claim 5
Dependent Claim 35 words
The membrane-type artificial lung of claim 1 in which the average thickness of a barrier layer in the membrane, calculated from the oxygen flux Q(O₂) and nitrogen flux Q(N₂), is not more than 10 micrometers.
Claim 6
Dependent Claim 20 words
The membrane-type artificial lung of claim 1 wherein the hollow fiber membrane has a porosity of 10 to 35 %.
Claim 7
Dependent Claim 20 words
The membrane-type artificial lung in which the ethanol flux of the hollow fiber membrane is not more than 30 ml/(min.m²).
Claim 8
Dependent Claim 20 words
The membrane-type artificial lung in which the ethanol flux of the hollow fiber membrane is not more than 30 ml/(min.m²).
Claim 9
Dependent Claim 30 words
The membrane-type artificial lung of claim 1 in which the hollow fiber membrane has an inside diameter of 100 to 300 micrometers and a thickness of 5 to 100 micro­meters.
Claim 10
Dependent Claim 30 words
The membrane-type artificial lung of claim 1 in which the hollow fiber membrane is used in the form of an assembly of hollow fibers sparsely aligned lengthwise and tied crosswise.
Claim 11
Independent Claim 96 words
A method of using a membrane-type artificial lung in which the membrane is a hollow fiber membrane which is composed mainly of a polyolefin, has an inside diameter of 10 to 500 micrometers, a thickness of 5 to 100 micrometers, a porosity of 7 to 50 % and an oxygen flux, Q(O₂), of at least 1 x 10⁻⁶ [cm³ (STP)/­(cm².sec.cmHg)] and is substantially impermeable to ethanol; which method comprises passing an oxygen-­containing gas over the inside of the membrane and blood over its outside, thereby performing exchange of gases between the blood and the oxygen-containing gas.
Claim 12
Independent Claim 96 words
A method of using a membrane-type artificial lung in which the membrane is a hollow fiber membrane which is composed mainly of a polyolefin, has an inside diameter of 10 to 500 micrometers, a thickness of 5 to 100 micrometers, a porosity of 7 to 50 % and an oxygen flux, Q(O₂), of at least 1 x 10⁻⁶ [cm³ (STP)/­(cm².sec.cmHg)] and is substantially impermeable to ethanol; which method comprises passing an oxygen-­containing gas over the inside of the membrane and blood over its outside, thereby performing exchange of gases between the blood and the oxygen-containing gas.
Claim 13
Independent Claim 96 words
A method of using a membrane-type artificial lung in which the membrane is a hollow fiber membrane which is composed mainly of a polyolefin, has an inside diameter of 10 to 500 micrometers, a thickness of 5 to 100 micrometers, a porosity of 7 to 50 % and an oxygen flux, Q(O₂), of at least 1 x 10⁻⁶ [cm³ (STP)/­(cm².sec.cmHg)] and is substantially impermeable to ethanol; which method comprises passing an oxygen-­containing gas over the outside of the membrane and blood over its inside, thereby performing exchange of gases between the blood and the oxygen-containing gas.
Claim 14
Independent Claim 96 words
A method of using a membrane-type artificial lung in which the membrane is a hollow fiber membrane which is composed mainly of a polyolefin, has an inside diameter of 10 to 500 micrometers, a thickness of 5 to 100 micrometers, a porosity of 7 to 50 % and an oxygen flux, Q(O₂), of at least 1 x 10⁻⁶ [cm³ (STP)/­(cm².sec.cmHg)] and is substantially impermeable to ethanol; which method comprises passing an oxygen-­containing gas over the outside of the membrane and blood over its inside, thereby performing exchange of gases between the blood and the oxygen-containing gas.

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