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EP0269175A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

A bone ingrowth chamber

Assignee: Nobel Biocare AB
•
Filing: 1987-11-16
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Granted: —
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Expires: 2007-11-16
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Abstract

Abstract The disclosure relates to an apparatus for studying the bone formation or bone ingrowth in an implant in response to locally administered test substances of different types. The apparatus is of a bio-compatible material, preferably pure titanium, and is intented to be implanted in living bone tissue, primarily for animal experiment activities. The apparatus consists of an outer portion (2) with a central recess (2a) in which an inner portion (5) is inserted. The two portions (2, 5) form, in the assembled state, a bone formation through channel (9, 10) which is exposed when the inner portion (5) is removed, whereby examination of tissue (24) which has grown into the channel (9, 10) is made possible. The inner portion (5) further comprises a reservoir (13) for the substance whose bone formation promoting properties are to be tested. The reservoir (13) is connected to the bone formation channel (9, 10) by the intermediary of a capillary aperture (14), so-called diffusion capillary, for the supply of the contemplated test substance without simultaneous liquid flow.

Inventors

  • 👤 Thomas Albrektsson
  • 👤 Per Aspenberg

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-22 23:51
CPC Classifications
A; A61; A61M; A61M39/00; A61M39/02; A61M39/0247; A61B; A61B10/00; A61B17/00; A61B17/56; A61B17/58; A61B17/68; A61F; A61F2/00; A61F2/02; A61F2/28; A61F2/30; A61F2/46; A61F2/468; A61B10/02; A61B10/0233; A61B10/025; A61F2/30767; A61F2002/2817; A61F2002/30001; A61F2002/30108; A61F2002/30199; A61F2002/30224; A61F2002/30235; A61F2002/30316; A61F2002/30329; A61F2002/30433; A61F2002/30667; A61F2002/30677; A61F2220/00; A61F2220/0025; A61F2220/0041; A61F2230/00; A61F2230/0063; A61F2230/0069; A61F2250/00; A61F2250/0058; A61F2250/0067; A61F2310/00; A61F2310/00005; A61F2310/00011; A61F2310/00023; A61F2310/00389; A61F2310/00395; A61F2310/00407; A61M2039/025; A61M2039/0267; A61M2039/0276; A61M2039/0294; A61M2210/00; A61M2210/02; Y; Y10; Y10S; Y10S623/00; Y10S623/912; Y10S623/914

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 122 words
An apparatus for studying bone formation growth in an implant in response to a locally administered test substance, the apparatus being of a bio-compatible material and being intended to be implanted in living bone tissue, characterized in that it consists of an outer portion (2) with a central recess (2a) and a removable inner portion (5) inserted in the recess, both portions together forming a bone formation through channel (9, 10) which is intended to be exposed when the inner portion (5) is removed, in order to make possible examination of tissue (24) ingrown into the channel, and said inner portion further including a reservoir (13) in communication with the bone ingrowth channel (9, 10) for the supply of the test substance.
Claim 2
Independent Claim 122 words
An apparatus for studying bone formation growth in an implant in response to a locally administered test substance, the apparatus being of a bio-compatible material and being intended to be implanted in living bone tissue, characterized in that it consists of an outer portion (2) with a central recess (2a) and a removable inner portion (5) inserted in the recess, both portions together forming a bone formation through channel (9, 10) which is intended to be exposed when the inner portion (5) is removed, in order to make possible examination of tissue (24) ingrown into the channel, and said inner portion further including a reservoir (13) in communication with the bone ingrowth channel (9, 10) for the supply of the test substance.
Claim 3
Dependent Claim 34 words
The apparatus as claimed in Claim 1, characterized in that it is manufactured of pure titanium, or at least coated with pure titanium on those surfaces which come into direct contact with bone tissue.
Claim 4
Dependent Claim 58 words
The apparatus as claimed in Claim 2, characterized in that the reservoir (13) consists of a cavity provided in the inner portion (5) and being in communication with the bone formation channel (9, 10) by the intermediary of a capillary aperture (14), so-called diffusion capillary, for the supply of the test substance under consideration without simultaneous liquid flow.
Claim 5
Dependent Claim 67 words
The apparatus as claimed in Claim 3, characterized in that the reservoir (13) consists of an elongate, diagonally disposed cavity of substantially the same orientation as the bone formation channel (9, 10) two through holes for locking screws (7, 8) for fixed interlocking of the two portions (2, 5) being disposed in the material of the inner portion (5) on either side of the elongate reservoir (13).
Claim 6
Dependent Claim 40 words
The apparatus as claimed in Claim 4, characterized in that the reservoir (13) is upwardly covered by a cover plate (15) which is locked to the upper end surface (16) of said inner portion by said locking screws (7, 8).
Claim 7
Dependent Claim 40 words
The apparatus as claimed in Claim 5, characterized in that said cover plate (15) is provided with two holes (19, 20) above said liquid reservoir (13) for hoses (21, 22) for the supply and removal (drainage), respectively of test substance.
Claim 8
Dependent Claim 35 words
The apparatus as claimed in Claim 6, characterized in that said reservoir (13) is connected to a subcutaneous, osmotically acting minipump (25) for the continuous supply of test substance during a predetermined period of time.

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