Patent FR2179166A1 successfully refreshed from Google Patents.
EP0268885A2
Expired / Lapsed
EP
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A process for controlled depolymerization of polysaccharides
Assignee: Ajorca SA
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Filing: 1987-11-04
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Granted: —
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Expires: 2007-11-04
Abstract
Abstract The present invention concerns to a novel process for a controlled chemical depolimerization of naturally occurring linear polysaccharides, more specifically glycosaminoglycans. The invention also embraces the depolimerized heparins obtained according to the new process and the pharmaceutical compositions containing such depolimerized heparins. The polysaccharides are subjected in accordance with the invention to the action of atomic oxygen which, preferably, is obtained from hypochlorous acid.
Inventors
- 👤 Victor Bautista Diaz
- 👤 Ricardo Hugo Domanico
- 👤 Fernando Fussi
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 11:36
CPC Classifications
C; C08; C08B; C08B37/00; C08B37/006; C08B37/0063; C08B37/0075; C08B37/0078
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
23 words
A chemical process for depolymerization of linear polysaccharides characterized by the fact that the polysaccharide was subjected to the action of atomic oxygen.
Claim 2
Dependent Claim
23 words
A chemical process for depolymerization of linear polysaccharides characterized by the fact that the polysaccharide was subjected to the action of atomic oxygen.
Claim 3
Dependent Claim
21 words
A method according to claim 1, characterized by the fact that the generation of atomic oxygen is obtained from hypochlorous acid.
Claim 4
Dependent Claim
15 words
A method according to claim 1, characterized by the fact that the polysaccharide is heparin.
Claim 5
Dependent Claim
28 words
A method according to claim 2, characterized by the fact that the pH range is 4 to 7 in aqueous solution and the temperature is 25°C to 100°C.
Claim 6
Dependent Claim
23 words
A method according to claim 1, characterized by the fact that the reaction is stopped at any time by addition of reducing agents.
Claim 7
Dependent Claim
22 words
A method according to claim 1, characterized by the fact that the product of the reaction is precipitated by a water-miscible solvent.
Claim 8
Dependent Claim
26 words
A process for preparing pharmaceutical compositions comprising combining depolymerized heparins obtained by the method described in claims 1 through 6 and a pharmaceutically effective carrier therefor.
References Cited (Backward Citations)
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