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EP0241178A1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Pharmaceutical composition for treating periodontal diseases

Assignee: Rohto Pharmaceutical Co Ltd
•
Filing: 1987-03-24
•
Granted: —
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Expires: 2007-03-24
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Abstract

Abstract A pharmaceutical composition for treating perio­dontal diseases which comprises one or more of therapeuti­cally active ingredients dispersed in a carrier, characte­rized in that said carrier consists of (A) water soluble polymer, and (B) polymeric particles having a limited solubility in water, said particles being dispersed in said water soluble polymer.

Inventors

  • 👤 Kiyotsugu Higashi
  • 👤 Shigeru Kametaka
  • 👤 Katsuhiko Morisaki
  • 👤 Shin'ichi Hayashi
  • 👤 Reiko Izumi

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 15:18
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0063

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 41 words
A pharmaceutical composition for treating periodontal diseases which comprises one or more of thera­peutically active ingredients dispersed in a carrier, characterized in that said carrier consists of (A) water soluble polymer, and (B) polymeric particles having a limited solubility in water,
Claim 2
Dependent Claim 41 words
A pharmaceutical composition for treating periodontal diseases which comprises one or more of thera­peutically active ingredients dispersed in a carrier, characterized in that said carrier consists of (A) water soluble polymer, and (B) polymeric particles having a limited solubility in water,
Claim 3
Dependent Claim 9 words
said particles being dispersed in said water soluble polymer.
Claim 4
Dependent Claim 9 words
said particles being dispersed in said water soluble polymer.
Claim 5
Dependent Claim 16 words
A pharmaceutical composition according to Claim 1 in the form of gel, sheet, film or bar.
Claim 6
Dependent Claim 133 words
A pharmaceutical composition according to Claim 1 or 2 wherein said particles are composed of one or more of compounds selected from ethyl cellulose, cellulose acetate, ethyl methacrylate / tri­methylammonioethyl methacrylate chloride copolymer, ion-­exchange resins, poly(glycolic acid), poly(lactic acid), polytetramethylglycolide, polydiethylglycolide, poly-ε-­caprolactone, poly(DL-decalactone), poly(alkyleneadipate), methyl acrylate / methacrylic acid copolymer, methyl acrylate / methacrylic acid / octylacrylate copolymer, ethyl acrylate / methacrylic acid copolymer, methyl acrylate / methacrylic acid / methylmethacrylate copolymer, methyl methacrylate / methacrylic acid copolymer, cellulose acetate phthalate, cellulose acetate succinate, cellulose acetate maleate, starch acetate phthalate, amylose acetate phtha­late, methyl cellulose phthalate, hydroxypropylmethyl cellulose phthalate, hydroxyethyl ethyl cellulose phthalate, hydroxypropylmethyl cellulose acetate succinate, carboxy­methylethyl cellulose, polyvinylalcohl phthalate, polyvinyl acetate phthalate, polyvinylacetal phthalate, polyvinyl­butylate phthalate, methyl methacrylate / dimethylaminoethyl methacrylate copolymer, polyvinylacetal / dimethylamino acetate, and cellulose acetate dibutylhydroxypropyl ether.
Claim 7
Dependent Claim 52 words
A pharmaceutical composition according to Claim 1, 2, or 3 wherein said water soluble polymer is selected from methyl cellulose, hydroxypropyl cellulose, sodium carboxymethylcellulose, hydroxypropyl­methyl cellulose, hydroxyethyl cellulose, sodium alginate, propylene glycol alginate, pullulan, tragacanth, xanthan gum, chitosan, polyethylene oxide, polyvinyl pyrrolidone, polyvinyl alcohol, polyacrylic acid, polymethacrylic acid, and a salt thereof.
Claim 8
Dependent Claim 21 words
A pharmaceutical composition according to any preceding claim wherein said particles have an average size ranging from 1µm to 500 µm.

References Cited (Backward Citations)

FR2148045A1 Cited
US4568535A Cited
EP0135022A2 Cited
DE3432573A1 Cited
EP0184389A2 Cited

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