EP0232955A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Anti-thrombogenic elastomer and objects and prostheses made therefrom
Assignee: Baylor College of Medicine
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Filing: 1987-01-06
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Granted: —
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Expires: 2007-01-06
Abstract
Abstract Disclosed are anti-thrombogenic compositions for making prostheses, prostheses made from these materials, methods of preparing these materials, to coating with the anti-thrombogenic composition objects made from materials other than prostheses which contact or come into contact with blood, and to surgical techniques utilizing them. The compositions include graphite present homogeneously in the matrix material rather than present as is colloidal graphite discretely dispersed within the matrix material. Numerous examples are set forth.
Inventors
- 👤 George P. Noon
- 👤 Louis W. Feldman
- 👤 Julia A. Peterson
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-22 23:15
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/40; A61L27/44; A61L27/443; A61L33/00; A61L33/02; A61L33/025
Claims Analysis
Total Claims: 41
Claim 1
Independent Claim
25 words
An anti-thrombogenic composition comprising, miscible material, powderized anti-thrombogenic material, the powderized anti-thrombogenic material homogeneously mixed with the miscible material thereby rendering the miosture anti-thrombogenic throughout.
Claim 2
Dependent Claim
25 words
An anti-thrombogenic composition comprising, miscible material, powderized anti-thrombogenic material, the powderized anti-thrombogenic material homogeneously mixed with the miscible material thereby rendering the miosture anti-thrombogenic throughout.
Claim 3
Dependent Claim
11 words
The composition of claim 1 wherein the miscible material is solidifiable.
Claim 4
Dependent Claim
13 words
The composition of claim 2 wherein the solidifiable material is silicone, urethane, acrylic.
Claim 5
Dependent Claim
11 words
The composition of claim 1 wherein the anti-thrombogenic material is carbon.
Claim 6
Dependent Claim
11 words
The composition of claim 4 wherein the carbon is graphite particles.
Claim 7
Dependent Claim
19 words
The composition of claim 5 wherein the gaphite particles range in size between about 3 to about 7 microns.
Claim 8
Dependent Claim
46 words
An anit-thrombogenic composition comprising, miscible solidifiable material, the miscible solidifiable material selected from the following: silicone, urethane or acrylic, powderized graphite particles ranging in size between about 3 to about 7 microns, the powderized graphite homogeneously mixed with the miscible material rendering the mixture anti-thrombogenic throughout.
Claim 9
Dependent Claim
46 words
An anit-thrombogenic composition comprising, miscible solidifiable material, the miscible solidifiable material selected from the following: silicone, urethane or acrylic, powderized graphite particles ranging in size between about 3 to about 7 microns, the powderized graphite homogeneously mixed with the miscible material rendering the mixture anti-thrombogenic throughout.
Claim 10
Dependent Claim
28 words
A process for preparing an anti-thrombogenic composition comprising, mixing miscible material in a container with powderized anti-thrombogenic material, the resulting mixture having the anti-thrombogenic material homogeneously present throughout.
Claim 11
Dependent Claim
28 words
A process for preparing an anti-thrombogenic composition comprising, mixing miscible material in a container with powderized anti-thrombogenic material, the resulting mixture having the anti-thrombogenic material homogeneously present throughout.
Claim 12
Dependent Claim
11 words
The process of claim 8 wherein the miscible material is solidifiable.
Claim 13
Dependent Claim
17 words
The process of claim 9 wherein the solidifiable material is selected from the following: silicone, urethane, acrylic.
Claim 14
Dependent Claim
11 words
The process of claim 8 wherein the anti-thrombogenic material is carbon.
Claim 15
Dependent Claim
12 words
The process of claim 11 wherein the anti-thrombogenic material is graphite particles.
Claim 16
Dependent Claim
19 words
The process of claim 12 wherein the graphite particles range in size from about 3 to about 7 microns.
Claim 17
Dependent Claim
13 words
The process of claim 8, including the step of solidifying the resulting mixture.
Claim 18
Dependent Claim
13 words
The process of claim 10 including the step of curing the solidifiable material.
Claim 19
Dependent Claim
9 words
An object made from the composition of claim 1.
Claim 20
Dependent Claim
9 words
An object made from the composition of claim 7.
Claim 21
Dependent Claim
12 words
The invention of claim 16 wherein the object is a prosthetic device.
Claim 22
Dependent Claim
12 words
The invention of claim 17 wherein the object is a prosthetic device.
Claim 23
Dependent Claim
145 words
A surgical process for connecting an artificial tubular graft to a natural tubular member, the process comprising, inserting the artificial tubular graft through an opening in a cylindrical hollow tie ring so that part of the artificial graft extends beyond the opening, folding back the extending part of the artificial graft over an outwardly extending front edge of the tie ring into a first recess between the front edge and a flange exending exteriorly from the middle of the tie ring, securing the folded back portion of the artificial graft in the first recess, introducing the artificial-graft-tie-ring structure into the natural tubluar member so that the natural tubular member covers the first recess and extends beyond it into a second recess formed between the flange and an upwardly extending rear edge of the tie ring, and securing the natural tubular member in the second recess.
Claim 24
Dependent Claim
145 words
A surgical process for connecting an artificial tubular graft to a natural tubular member, the process comprising, inserting the artificial tubular graft through an opening in a cylindrical hollow tie ring so that part of the artificial graft extends beyond the opening, folding back the extending part of the artificial graft over an outwardly extending front edge of the tie ring into a first recess between the front edge and a flange exending exteriorly from the middle of the tie ring, securing the folded back portion of the artificial graft in the first recess, introducing the artificial-graft-tie-ring structure into the natural tubluar member so that the natural tubular member covers the first recess and extends beyond it into a second recess formed between the flange and an upwardly extending rear edge of the tie ring, and securing the natural tubular member in the second recess.
Claim 25
Dependent Claim
23 words
The process of claim 20 wherein the artificial tubular graft is an arterial graft and the natural tubular member is a bodily artery.
Claim 26
Dependent Claim
17 words
The process of claim 20 wherein the arterial graft is made from the composition of claim 1.
Claim 27
Dependent Claim
17 words
The process of claim 20 wherein the arterial graft is made from the composition of claim 7.
Claim 28
Dependent Claim
21 words
The process of claim 20 wherein a tied suture is used to secure the portions in the first and second recesses.
Claim 29
Dependent Claim
26 words
The process of claim 20 wherein a suture with knots spaced along its length is used to tie the natural tubular member in the second recess.
Claim 30
Dependent Claim
44 words
A tie ring for connecting a tubular graft to a natural tubular member, the tie ring comprising a hollow cylindrical body member having outwarly extending edges formed integrally at each end thereof and an outwardly extending flange formed integrally thereof between the two edges.
Claim 31
Dependent Claim
44 words
A tie ring for connecting a tubular graft to a natural tubular member, the tie ring comprising a hollow cylindrical body member having outwarly extending edges formed integrally at each end thereof and an outwardly extending flange formed integrally thereof between the two edges.
Claim 32
Dependent Claim
13 words
The tie ring of claim 26 formed of the composition of claim 1.
Claim 33
Dependent Claim
13 words
The tie ring of claim 26 formed of the composition of claim 7.
Claim 34
Dependent Claim
14 words
A woven structure formed of weaveable strands made from the composition of claim 1.
Claim 35
Dependent Claim
14 words
A woven structure formed of weaveable strands made from the composition of claim 7.
Claim 36
Dependent Claim
12 words
A tubular hollow arterial graft made from the composition of claim 1.
Claim 37
Dependent Claim
32 words
A tubular hollow arterial graft made from the omposition of claim 2 wherein the solidifiable material is rubber or rubber-like having self-sealing ability and is cured sufficiently to render the graft flexible.
Claim 38
Dependent Claim
20 words
The graft of claim 32 wherein reinforcing material is wrapped around the outside of the graft to increase its strength.
Claim 39
Dependent Claim
45 words
A material structure having a first layer and a second layer spaced apart from the first layer, the first layer being made of the composition of claim 1, and the second layer being made of another material to which the first layer can be adhered.
Claim 40
Dependent Claim
13 words
The material structure of claim 34 wherein the second layer has self-sealing ability.
Claim 41
Dependent Claim
62 words
A material structure having a first layer, a second layer, and an intermediate layer, the first layer made of the composition of claim 1, the second layer being made of a material with self-sealing ability, and the intermediate layer having the powderized anti-thrombogenic material mixed therein so that the amount of it gradually decreases from the first layer to the second layer.
References Cited (Backward Citations)
No citation records indexed.
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