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EP0227627A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Composition and method for osseous repair

Assignee: University of Minnesota Twin Cities
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Filing: 1986-12-18
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Granted: —
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Expires: 2006-12-18
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Abstract

Abstract A composition and method for the repair of an osseous defect comprising introducing into said defect a phosphophoryn calcium salt, preferably in combination with a matrix material such as type I collagen.

Inventors

  • 👤 John J. Sauk
  • 👤 Craig L. Van Kampen

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 04:20
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/14; A61L27/22; A61L27/227; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/39; A61L24/00; A61L24/04; A61L24/043; A61L24/10; A61L24/102; A61L2430/00; A61L2430/38

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 24 words
A composition comprising an amount of a phosphophoryn calcium salt effective to promote new bone formation upon introduction of the composition into osseous defects.
Claim 2
Dependent Claim 24 words
A composition comprising an amount of a phosphophoryn calcium salt effective to promote new bone formation upon introduction of the composition into osseous defects.
Claim 3
Dependent Claim 14 words
The composition of claim 1 wherein the composition comprises a dentinal phosphophoryn calcium salt.
Claim 4
Dependent Claim 12 words
The composition of claim 1 wherein the composition comprises type I collagen.
Claim 5
Dependent Claim 22 words
The composition of claim 3 wherein the weight ratio of the phosphophoryn calcium salt to the type I colla­gen is about 3.0-0.1:1.
Claim 6
Dependent Claim 22 words
The composition of claim 4 wherein the weight ratio of the phosphophoryn calcium salt to the type I colla­gen is about 1:1.
Claim 7
Dependent Claim 28 words
A composition comprising a mixture of a phosphophoryn calcium salt and type I collagen effective to promote new bone formation upon introduction of the com­position into osseous defects.
Claim 8
Dependent Claim 28 words
A composition comprising a mixture of a phosphophoryn calcium salt and type I collagen effective to promote new bone formation upon introduction of the com­position into osseous defects.
Claim 9
Dependent Claim 14 words
The composition of claim 6 wherein the mixture comprises a dentinal phosphophoryn calcium salt.
Claim 10
Dependent Claim 23 words
The composition of claim 7 wherein the weight ratio of the dentinal phosphophoryn calcium salt to the type I collagen is about 2.5-0.5:1.
Claim 11
Dependent Claim 23 words
The composition of claim 8 wherein the weight ratio of the dentinal phosphophoryn calcium salt to the type I collagen is about 1:1.
Claim 12
Independent Claim 30 words
A method for the repair of an osseous defect comprising introducing into said defect a composition comprising an amount of a phosphophoryn calcium salt effec­tive to promote new bone formation.
Claim 13
Independent Claim 30 words
A method for the repair of an osseous defect comprising introducing into said defect a composition comprising an amount of a phosphophoryn calcium salt effec­tive to promote new bone formation.
Claim 14
Independent Claim 34 words
A method for the repair of an osseous defect comprising introducing into said defect a composition comprising a mixture of a phosphophoryn calcium salt and type I collagen effective to promote new bone formation.
Claim 15
Independent Claim 34 words
A method for the repair of an osseous defect comprising introducing into said defect a composition comprising a mixture of a phosphophoryn calcium salt and type I collagen effective to promote new bone formation.

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