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EP0211267A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Continuous release peptide compositions

Assignee: Wyeth Holdings LLC
•
Filing: 1986-07-10
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Granted: —
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Expires: 2006-07-10
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Abstract

Abstract The Invention relates to compositions for the parenteral sdministrotion of an essentially uniform and continuous amount of a peptide composition over an extended period of time. The invention also relates to the preparation and administration of said peptide compositions.

Inventors

  • 👤 Susan Mancini Cady
  • 👤 Richard Fishbein

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 13:54
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/04; A61K38/08; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; C; C07; C07K; C07K14/00; C07K14/435; C07K14/575; C07K14/60; C07K7/00; C07K7/04; C07K7/06

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 46 words
A composition for the parenteral administration of an essentially uniform and continuous amount of a peptide over an extended period of time which comprises a compacted and partially coated fatty acid salt of the peptide, which exhibits some degree of solubility in an aqueous physiological environment.
Claim 2
Dependent Claim 46 words
A composition for the parenteral administration of an essentially uniform and continuous amount of a peptide over an extended period of time which comprises a compacted and partially coated fatty acid salt of the peptide, which exhibits some degree of solubility in an aqueous physiological environment.
Claim 3
Dependent Claim 31 words
A composition according to Claim 1, wherein the coating is biodegradable or non-biodegradable, the fatty acid salt is selected from a C 10 -C 20 fatty acid, and the peptide is
Claim 4
Dependent Claim 11 words
A composition according to Claim 2, wherein the salt is tristearate.
Claim 5
Independent Claim 45 words
A method for administering parenterally an essentially uniform and continuous amount of a peptide over an extended period of time which comprises implanting a compacted and partially coated fatty acid salt of the peptide, which exhibits some degree of solubility in an aqueous physiological environment.
Claim 6
Independent Claim 45 words
A method for administering parenterally an essentially uniform and continuous amount of a peptide over an extended period of time which comprises implanting a compacted and partially coated fatty acid salt of the peptide, which exhibits some degree of solubility in an aqueous physiological environment.
Claim 7
Dependent Claim 30 words
A method according to Claim 4, wherein the coating is biodegradable or non-biodegradable, the fatty acid is selected from a C IO -C 20 fatty acid, and the peptide is
Claim 8
Dependent Claim 12 words
A method according to Claim 5, wherein the salt is the tristearate.
Claim 9
Independent Claim 76 words
A method for preparing an implant for the parenteral administration of an essentially uniform and continuous amount of a peptide over an extended period of time which comprises compacting a fatty acid salt of the peptide, which exhibits some degree of solubility in an aqueous physiological environment, into the form of an implant; coating the implant with a coating material; and removing a section of the coating material from the coated implant to expose the peptide.
Claim 10
Independent Claim 76 words
A method for preparing an implant for the parenteral administration of an essentially uniform and continuous amount of a peptide over an extended period of time which comprises compacting a fatty acid salt of the peptide, which exhibits some degree of solubility in an aqueous physiological environment, into the form of an implant; coating the implant with a coating material; and removing a section of the coating material from the coated implant to expose the peptide.
Claim 11
Dependent Claim 30 words
A method according to Claim 7, wherein the coating is biodegradable or non-biodegradable, the fatty acid is selected from a C 10 -C 20 fatty acid, and the peptide is
Claim 12
Dependent Claim 11 words
A method according to Claim 8, wherein the salt is tristearate.

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