EP0182689A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Apparatus for angioplasty
Assignee: Beth Israel Deaconess Medical Center
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Filing: 1985-10-24
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Granted: —
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Expires: 2005-10-24
Abstract
Abstract @ The region surrounding the balloon utilized in percutaneous transluminal coronary angioplasty is heated by means (66) within the balloon or within the skin of the balloon upon inflation of the balloon such that disrupted tissues of the plaque in the arterial wall are heated in order to fuse together fragmented segments of tissue and to coagulate blood trapped within dissected planes of tissue and within fissures created by wall fracture such that upon subsequent balloon deflation a smooth cylindrically-shaped channel results, thereby to prevent collapse of any flap of material which could cause either abrupt arterial closure and an acute myocardial infarction or gradual restenosis at the site of balloon inflation.
Inventors
- 👤 J. Richard Spears
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 12:40
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/104; A61B; A61B17/00; A61B17/22; A61B18/00; A61B18/04; A61B18/08; A61B18/082; A61B18/18; A61B18/20; A61B18/22; A61B18/24; A61B18/245; A61B2017/22001; A61B2017/22002; A61B2017/22051; A61B2017/22061; A61B2017/22062; A61B2017/22064; A61B2018/00315; A61B2018/00559; A61B2018/044; A61B2018/046; A61B18/06; A61B2018/068; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06
Claims Analysis
Total Claims: 62
Claim 1
Independent Claim
5 words
WHAT IS CLAIMED IS :
Claim 2
Independent Claim
100 words
A method for preventing abrupt reclosure and restenosis in percutaneous transluminal coronary angioplasty comprising the steps of : providing a balloon in the coronary artery at the region of coronary narrowing ; inflating the balloon with fluid; and providing heat at the region surrounding the inflated balloon sufficient to fuse together segments of tissue in said region and to coagulate blood trapped within dissection planes of tissues and within fissures created by wall fracture in said region; and deflation and removal of said balloon thereby to provide a smooth cylindrically-shaped channel which prevents collapse of material into the coronary artery.
Claim 3
Dependent Claim
20 words
The method of claim 1, wherein said heat is provided by monochromatic radiation injected into the interior of said balloon.
Claim 4
Dependent Claim
27 words
The method of claim 2, wherein said monochromatic radiation heats material within the balloon, with the heat thus generated being transferred to the region surrounding the balloon.
Claim 5
Dependent Claim
54 words
The method of claim 2,wherein said balloon and fluid utilized to inflate said balloon is transparent to radiation of a predetermined wavelength and wherein said heat is provided at said region by radiation which passes through the balloon wall and is absorbed by blood and other arterial tissue in the region surrounding the balloon.
Claim 6
Dependent Claim
25 words
The method of claim 1, wherein the surface of said balloon is provided with wires, said wires being heated by passage of electric current therethrough.
Claim 7
Dependent Claim
36 words
6 . The method of claim 1, wherein resistance heating means are provided in the balloon and wherein said region is heated by the passage of electrical current through the resistance heating means with the balloon.
Claim 8
Dependent Claim
74 words
The method of claim 1, wherein the heat delivered to the region adjacent the balloon is provided by transmitting energy to a region within the balloon via fiber optics having a light disseminating termination, with said fiber optics including means within the balloon for causing energy transmitted down the fiber optics to be emitted radially and homogeneously along the long axis of the light disseminating termination of the optical fiber within the inflated balloon.
Claim 9
Dependent Claim
16 words
The method of claim 1, wherein said steps are utilized after conventional percutaneous transluminal coronary angioplasty.
Claim 10
Dependent Claim
18 words
The method of claim 1, wherein said steps are utilized in lieu of conventional percutaneous transluminal coronary angioplasty.
Claim 11
Dependent Claim
18 words
The method of claim 1, wherein the liquid within the balloon is heated by a chemical exothermic reaction.
Claim 12
Dependent Claim
17 words
The method of claim 10, wherein said chemical exothermic reaction includes the dissolution of magnesium sulfate powder.
Claim 13
Dependent Claim
20 words
The method of claim 10, wherein said chemical exothermic reaction includes the interaction of silver chloride and sodium hydroxide solutions.
Claim 14
Dependent Claim
39 words
The method of claim 1, wherein said balloon is filled with a biocompatible gas, with the energy inserted into the balloon being absorbed only by the balloon material, or other absorbing surface provided within the body of the balloon.
Claim 15
Dependent Claim
39 words
The method of claim 1, wherein the plaque, the normal arterial wall, blood within the arterial wall or any or all of these tissues are heated directly without first heating either the fluid within the balloon or the'balloon material.
Claim 16
Dependent Claim
41 words
The method of claim 1, and further including sensing the intra-arterial sound produced by vaporization of tissue or liquid boiling, thereby to permit limiting power delivery to a level which is sufficient to achieve tissue fusion, but below the vaporization/boiling threshold.
Claim 17
Independent Claim
65 words
A method of preventing abrupt reclosure and restenosis comprising the step of providing a smooth enlarged lumen composed of fused tissue elements of the arterial wall in the region of a coronary narrowing, whereby the incidence of restenosis is reduced because of more favorable flow patterns produced by the smooth lumen and because the fused tissue elements of the arterial wall are incapable of proliferation.
Claim 18
Dependent Claim
32 words
The method of claim 16, wherein the region of coronary narrowing is opened due to the utilization of an inflated balloon inserted through the artery and positioned at the narrowed portion thereof.
Claim 19
Dependent Claim
23 words
The method of claim 17, wherein said smooth lumen is formed via heat transmitted from the balloon surface to the immediately adjacent region.
Claim 20
Dependent Claim
24 words
The method of claim 17, wherein the smooth lumen is formed via energy transmitted into the region immediately adjacent the surface of the balloon.
Claim 21
Dependent Claim
100 words
The method of claim 16, wherein a balloon is utilized at the coronary narrowing and wherein the balloon is filled with transparent fluid and wherein the balloon is transparent to radiation of a predetermined wavelength, said fused material being provided through the utilization of an optical fiber with a portion positioned at the balloon, the fiber having a light disseminating termination at the interior of the balloon structure, the method further including the injection of laser light into one end of the fiber which laser light is transmitted through the liquid and balloon to the surrounding tissue which contains blood.
Claim 22
Dependent Claim
12 words
The method of claim 20, wherein said predetermined wavelength is 1.06 microns.
Claim 23
Dependent Claim
18 words
The method of claim 20, wherein said predetermined wavelength includes the several wavelengths produced by an argon-ion laser.
Claim 24
Dependent Claim
19 words
The method of claim 20, wherein the balloon is filled with a fluid which absorbs a specific laser wavelength.
Claim 25
Dependent Claim
22 words
The method of claim 20, wherein biocompatible pigments including Evan's Blue, methylene blue and Congo red are utilized in the balloon inflation.
Claim 26
Dependent Claim
14 words
The method of claim 20, wherein the fluid utilized in the balloon is water.
Claim 27
Dependent Claim
14 words
The method of claim 25, wherein 10.6 micron radiation is injected into the water.
Claim 28
Dependent Claim
104 words
Apparatus for preventing acute abrupt reclosure and restenosis in percutaneous transluminal coronary angioplasty comprising : a balloon in the coronary artery at the region of coronary narrowing ; means for inflating the balloon with fluid ; means for providing heat at the region sourrounding the inflated balloon sufficient to fuse together segments of tissue in said region and to coagulate blood trapped within dissection planes of tissue and within fissures created by wall fracture in said region; and means for deflation and removal of said balloon, thereby to provide a smooth cylindrically - shaped channel which prevents collapse of material into the coronary artery.
Claim 29
Dependent Claim
19 words
The apparatus of claim 27, and further including means for injecting monochromatic radiation into the interior of said balloon.
Claim 30
Dependent Claim
30 words
The apparatus of claim 28 and further including material within said balloon heated by said monochromatic radiation, with the heat thus generated being transferred to the region surrounding the balloon.
Claim 31
Dependent Claim
51 words
The apparatus of claim 28, wherein said balloon and fluid utilized to inflate said balloon are transparent to radiation of a predetermined wavelength and wherein said heat is provided at said region via radiation which passes through the balloon wall and is absorbed by blood in the region surrounding the balloon.
Claim 32
Dependent Claim
28 words
The apparatus of claim 27, wherein the surface of said balloon is provided with wires, and means for passing electric current through said wires to heat said wires.
Claim 33
Dependent Claim
30 words
32 . The apparatus of claim 27, and further including resistance heating means in the balloon and means for providing electrical current through the resistance heating means within the balloon.
Claim 34
Dependent Claim
44 words
The apparatus of claim 27, and further including fiber optic cables having a portion positioned within the balloon, with said fiber optic cable including means within the balloon for causing energy transmitted down the fiber optic cable to radiate radially within the inflated balloon.
Claim 35
Dependent Claim
18 words
The apparatus of claim 27, wherein the liquid within the balloon is heated by a chemical exothermic reaction.
Claim 36
Dependent Claim
17 words
The apparatus of claim 34, wherein said chemical exothermic reaction includes the dissolution of magnesium sulfate powder.
Claim 37
Dependent Claim
20 words
The apparatus of claim 34, wherein said chemical exothermic reaction includes the interaction of silver chloride and sodium hydroxide solutions.
Claim 38
Dependent Claim
39 words
The apparatus of claim 27, wherein said balloon is filled with a biocompatible gas with the energy delivered to the balloon being absorbed only by the balloon material, or other absorbing surface provided within the body of the balloon.
Claim 39
Dependent Claim
38 words
The apparatus of claim 27, wherein the plaque, the normal arterial wall, blood within the arterial wall or all of these tissues are heated directly without first heating either the fluid within the balloon or the balloon material.
Claim 40
Dependent Claim
43 words
The apparatus of claim 27, and further including means for sensing the intra-arterial sound produced by vaporization of tissue or liquid boiling, thereby to permit limiting power delivery to a level which is sufficient to achieve tissue fusion, but below the vaporization/boiling threshold.
Claim 41
Dependent Claim
62 words
Apparatus for preventing acute abrupt reclosure and restenosis comprising means for providing a smooth enlarged lumen composed of fused elements of the arterial wall in the region of a coronary narrowing, whereby the incidence of restenosis is reduced because of more favorable flow patterns produced by the smooth lumen and because the fused elements of the arterial wall are incapable of proliferation.
Claim 42
Dependent Claim
23 words
The apparatus of claim 40, wherein said smooth lumen is formed via heat transmitted from the balloon surface to the immediately adjacent region.
Claim 43
Dependent Claim
25 words
The apparatus of claim 40, wherein the enlarged smooth lumen is formed via energy transmitted into the region immediately adjacent the surface of the balloon.
Claim 44
Dependent Claim
68 words
The apparatus of claim 40, including a balloon utilized at the coronary narrowing, the balloon being filled with transparent fluid, the balloon being transparent to radiation of a predetermined wavelength ; an optical fiber having a portion positioned at the balloon, said fiber including a light disseminating termination at the interior of the balloon structure ; and means for injecting laser light into one end of said fiber.
Claim 45
Dependent Claim
12 words
The apparatus of claim 43, wherein said predetermined wavelength is 1.06 microns.
Claim 46
Dependent Claim
19 words
The apparatus of claim 43, wherein the balloon is filled with a fluid which absorbs a specific laser wavelength.
Claim 47
Dependent Claim
22 words
The apparatus of claim 43, wherein biocompatible pigments including Evans Blue, methylene blue and Congo red are utilized in the balloon inflation.
Claim 48
Dependent Claim
14 words
The apparatus of claim 43, wherein the fluid utilized in the balloon is water.
Claim 49
Dependent Claim
15 words
The apparatus of claim 47, wherein 10.6 micron laser light is injected into the water.
Claim 50
Dependent Claim
17 words
The apparatus of claim 43, wherein said predetermined wavelength includes the several wavelengths of an argon-ion laser.
Claim 51
Dependent Claim
40 words
A process for remodelling a tissue material comprising the steps of : altering a tissue material configuration to provide a reconfigured tissue material shape; and thermally fusing the reconfigured tissue material to cause retention of the reconfigured tissue material shape.
Claim 52
Dependent Claim
18 words
The process of claim 50, wherein said altering step includes the step of expanding a plaque restricted vessel.
Claim 53
Dependent Claim
21 words
The process of claim 51, wherein said altering step further includes the step of pressing the plaque into surrounding vessel tissue.
Claim 54
Dependent Claim
21 words
The process of claim 52, wherein the fusing step includes the step of fusing the plaque in the surrounding vessel tissue.
Claim 55
Dependent Claim
28 words
The process of claim 50, wherein said altering step includes the step of pressing a tissue anonomally into a surrounding tissue area to define said reconfigured tissue shape.
Claim 56
Dependent Claim
14 words
The process of claim 50, wherein said tissue material is collagen containing tissue material.
Claim 57
Independent Claim
44 words
A system for remodelling a tissue material comprising the steps of : means for altering a tissue material configuration to provide a reconfigured tissue material shape; and means for thermally fusing the reconfigured tissue material to cause retention of the reconfigured tissue material shape.
Claim 58
Dependent Claim
18 words
The system of claim 56, wherein said means for altering includes means for expanding a plaque restricted vessel.
Claim 59
Dependent Claim
21 words
The system of claim 57, wherein said means for altering further includes means for pressing the plaque into surrounding vessel tissue.
Claim 60
Dependent Claim
21 words
The system of claim 58, wherein the means for fusing includes means for fusing the plaque in the surrounding vessel tissue.
Claim 61
Dependent Claim
28 words
The system of claim 58, wherein said means for altering includes means for pressing a tissue anonomally into a surrounding tissue area to define said reconfigured tissue shape.
Claim 62
Dependent Claim
14 words
The system of claim 58, wherein said tissue material is collagen containing tissue material.
References Cited (Backward Citations)
No citation records indexed.
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