EP0171176B1
Expired / Lapsed
EP
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Bone repair using collagen
Assignee: Collagen Aesthetics Inc
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Filing: 1985-07-03
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Granted: 1991-10-02
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Expires: 2005-07-03
Abstract
No abstract record available.
Inventors
- 👤 Donald G. Wallace
- 👤 Karl A. Piez
- 👤 Thomas L. Smestad
- 👤 Saeid Seyedin
- 👤 John M. Mcpherson
- 👤 Rosa Armstrong
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 11:24
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/78; A; A61; A61F; A61F2/00; A61F2/02; A61F2/28; A61L; A61L27/00; A61L27/14; A61L27/22; A61L27/24; A61F2310/00; A61F2310/00005; A61F2310/00365; A61K; A61K38/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
42 words
A composition for effecting conductive repair of a bone defect in a mammal which includes a demineralized Type I collagen preparation characterized in that the preparation consists essentially of a collagen powder which is a protease-treated demineralized bone powder free of lipids.
Claim 2
Dependent Claim
16 words
A composition according to Claim 1 which includes also a purified atelopeptide reconstituted fibrillar skin collagen.
Claim 3
Dependent Claim
17 words
Type I collagen powder characterized in that it is a demineralized, protease-treated bone powder free of lipids.
Claim 4
Dependent Claim
45 words
A process for preparing a demineralized Type I collagen preparation characterized in that, to prepare a collagen powder which is a protease-treated demineralized bone powder free of lipids, demineralized bone powder is treated with at least one protease other than collagenase to remove proteinaceous components.
Claim 5
Dependent Claim
11 words
A process according to Claim 4 wherein the protease is trypsin.
Claim 6
Dependent Claim
36 words
A process according to Claim 4 or Claim 5 including obtaining a collagen - containing residue after the treatment with the protease, recovering the residue and extracting it with a solvent to free it from lipids.
Claim 7
Dependent Claim
11 words
A process according to Claim 6 wherein the solvent is acetone.
Claim 8
Dependent Claim
23 words
A process according to any one of Claims 4 to 7 which includes enzymatically treating the demineralized bone to remove non-proteinaceous bone components.
Claim 9
Dependent Claim
19 words
A process according to any one of Claims 4 to 8 including the further step of sterilizing the powder.
References Cited (Backward Citations)
No citation records indexed.
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