EP0161887A2
Expired / Lapsed
EP
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Crosslinked hyaluronic acid and its use
Assignee: Seikagaku Corp
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Filing: 1985-05-03
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Granted: —
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Expires: 2005-05-03
Abstract
Abstract Crosslinked hyaluronic acid or salts thereof prepared by crosslinking hyaluronic acid or salts thereof with a polyfunctional epoxy compound wherein a crosslinking index or number is 5 or more per 1000 repeating disaccharides composed of glucronic acid in hyaluronic acid and N-acetylglucosamine, and having various medical and cosmetic uses.
Inventors
- 👤 Katukiyo C/O Tokyo Kenkyusho Sakurai
- 👤 Yoshio C/O Tokyo Kenkyusho Ueno
- 👤 Takashi C/O Tokyo Kenkyusho Okuyama
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 19:28
CPC Classifications
C; C08; C08B; C08B37/00; C08B37/006; C08B37/0063; C08B37/0075; A; A61; A61K; A61K8/00; A61K8/18; A61K8/72; A61K8/73; A61K8/735; A61K9/00; A61K9/70; A61L; A61L31/00; A61L31/04; A61L31/042; A61L31/043; A61L31/044; A61Q; A61Q19/00; C08B37/0072; C08L; C08L5/00; C08L5/08; A61Q5/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
43 words
A crosslinked hyaluronic acid or a salt thereof obtainable by crosslinking hyaluronic acid or a salt thereof with a polyfunctional epoxy compound, wherein a crosslinking index is 5 or more per 1000 repeating disaccharides composed of glucuronic acid in hyaluronic acid and N-acetylglucosamine.
Claim 2
Dependent Claim
43 words
A crosslinked hyaluronic acid or a salt thereof obtainable by crosslinking hyaluronic acid or a salt thereof with a polyfunctional epoxy compound, wherein a crosslinking index is 5 or more per 1000 repeating disaccharides composed of glucuronic acid in hyaluronic acid and N-acetylglucosamine.
Claim 3
Dependent Claim
28 words
A crosslinked hyaluronic acid or a salt thereof as claimed in Claim 1 wherein it has non-Newtonian index of 0.5 - 0.8 and shows water solubility and stringiness.
Claim 4
Dependent Claim
34 words
A crosslinked hyaluronic acid or a salt thereof as claimed in Claim 1 wherein said crosslinking index is 10 or more per 1000k repeating disaccharides composed of glucuronic acid in hyaluronic acid and N-acetylglucosamine.
Claim 5
Dependent Claim
36 words
A pharmaceutical composition for treating arthritides comprising as an active ingredient in combination with a carrier or diluent, wherein said active ingredient is a crosslinked hyaluronic acid or a salt thereof as claimed in Claim 1.
Claim 6
Dependent Claim
40 words
A pharmaceutical composition for applying to vitreous body comprising as an active ingredient in combination with an ophthanologically acceptable carrier or diluent, wherein said active ingredient is a crosslinked hyaluronic acid or a salt thereof as claimed in Claim 1.
Claim 7
Dependent Claim
29 words
A cosmetic composition for applying to skin comprises a crosslinked hyaluronic acid or a salt thereof as claimed in'Claim 1 in combination with a cosmetically acceptable carrier or diluent.
Claim 8
Dependent Claim
21 words
A molding composition for medical molded product comprises a crosslinked hyaluronic acid or a salt thereof as claimed in Claim 1.
References Cited (Backward Citations)
No citation records indexed.
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