Patent EP0500289A1 successfully refreshed from Google Patents.
EP0150960A2
Expired / Lapsed
EP
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Catheter for retroinfusion of pharmacologic agents
Assignee: Corday Eliot Dr
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Filing: 1985-01-17
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Granted: —
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Expires: 2005-01-17
Abstract
Abstract @ An inflatable catheter and method of medical treatment in which the flexible balloon material stretches when inflated to produce an acorn-shaped balloon, the broadened base of which seals against the vein interfacing the coronary sinus orifice of the heart to allow for stoppage of the natural flow of blood in the vessel, and which facilitates anterograde controlled, synchronous retroinfusion of pharmacologic or angiographic agent into the myocardium. An inflated catheter and method of medical treatment in which the apex of the inflated acorn-shaped balloon tapers away from the walls of the coronary sinus to prevent blockage of fluid flow through the middle cardiac vein thereby preventing pressure build up and edema in the myocardium.
Inventors
- 👤 Eliot Corday
- 👤 Samuel Meerbaum
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 03:20
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/1002; A61M2025/1043; A61M2025/1052
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
180 words
A catheter apparatus for retroinfusion of fluids into the coronary sinus for treatment or diagnosis of the myocardium comprising: a hollow, flexible fluid delivery tube adapted to pass through the coronary sinus orifice and into the coronary sinus for delivery therethrough of pharmacologic fluids; a balloon catheter material adapted for inflation and secured and sealed just proximally to the distal extension of said hollow fluid delivery tube, said balloon material having a broadened base and narrow tapered apex when inflated, the base of said inflated balloon adapted to seal about the vein interfacing the coronary sinus orifice, and the apex portion of said inflated balloon tapering away from the walls of the vessel toward the center of the coronary sinus in order to avoid obstructing the middle cardiac vein to prevent pressure build up and edema and to facilitate drainage of the coronary sinus during cardiac systole; means for delivery of fluid into said hollow fluid delivery tube; means for securing said balloon material to the distal extension of said fluid delivery tube; and means for inflating said balloon material.
Claim 2
Dependent Claim
180 words
A catheter apparatus for retroinfusion of fluids into the coronary sinus for treatment or diagnosis of the myocardium comprising: a hollow, flexible fluid delivery tube adapted to pass through the coronary sinus orifice and into the coronary sinus for delivery therethrough of pharmacologic fluids; a balloon catheter material adapted for inflation and secured and sealed just proximally to the distal extension of said hollow fluid delivery tube, said balloon material having a broadened base and narrow tapered apex when inflated, the base of said inflated balloon adapted to seal about the vein interfacing the coronary sinus orifice, and the apex portion of said inflated balloon tapering away from the walls of the vessel toward the center of the coronary sinus in order to avoid obstructing the middle cardiac vein to prevent pressure build up and edema and to facilitate drainage of the coronary sinus during cardiac systole; means for delivery of fluid into said hollow fluid delivery tube; means for securing said balloon material to the distal extension of said fluid delivery tube; and means for inflating said balloon material.
Claim 3
Dependent Claim
53 words
The catheter claimed in Claim 1 wherein said fluid is selected from the group consisting of prostaglandins, mannitol, streptokinase, lidocaine, procainamide, verapamil, propranolol, disopyramide, amiodarone, cardiazam, nifedipine, dipyridamole, novocaine, aminophyllin, digitalis, catecholamines, steroids, tissue plasminogen activators, glucose-insulin-potassium mixtures, arterial blood and diagnostic contrast agents employed for angiography, radionuclide imaging or noniodinated echocardiographic imaging.
Claim 4
Dependent Claim
29 words
The catheter claimed in Claim 1 wherein said balloon material is secured and sealed 1 to 4 centimeters proximally to the distal extension of said hollow fluid delivery tube.
Claim 5
Dependent Claim
36 words
The catheter claimed in Claim 1 wherein said means for delivery of fluid into said hollow fluid delivery tube consists of a gravity-feed infusion container adapted for controlled delivery of fluids into said fluid delivery tube.
Claim 6
Dependent Claim
34 words
The catheter claimed in Claim 1 wherein said means for delivery of fluid consists of a medical infusion pump for controlled administration of specified quantities of pharmacologic fluids into said hollow fluid delivery tube.
Claim 7
Dependent Claim
43 words
The catheter claimed in Claim 1 wherein said means for securing said balloon material to the distal extension of said catheter body consists of application of cement to bind the balloon material to the catheter fluid delivery tube, and applying ligatures for reinforcement.
Claim 8
Dependent Claim
87 words
The catheter claimed in Claim 1 wherein the means for inflating said balloon material consists of small orifices located in the hollow fluid delivery tube and disposed in the area of the cavity formed by the balloon material when sealed and secured at the distal extension of said hollow fluid delivery tube, said orifices providing channels allowing for conveyance of fluid from said hollow fluid delivery tube into the cavity formed by said balloon material and facilitating thereby inflation of the catheter balloon by the infusing fluid.
Claim 9
Dependent Claim
81 words
The catheter claimed in Claim 1 wherein said means for inflating said balloon material consists of a second hollow small lumen tube structurally connected to said fluid delivery tube, the distal extension of which is disposed inside the cavity formed by the balloon material when secured and sealed to said hollow fluid delivery tube, said small lumen inflating tube thereby facilitating the conveyance of fluid into the balloon cavity thereby inflating said catheter balloon by the flow of pressurized infusing fluid.
Claim 10
Dependent Claim
35 words
The catheter claimed in Claim 1 further comprising: means to monitor the myocardial beat and to administer fluids through said catheter in a pulsatile manner following each heart beat when the heart is in diastole.
Claim 11
Dependent Claim
18 words
The catheter claimed in Claim 9 wherein said means to monitor the myocardial beat consists of an electrocardiograph.
Claim 12
Dependent Claim
101 words
The catheter claimed in Claim 9 wherein said means to administer fluids in a pulsatile manner consists of a synchronous gas-actuated bladder pump disposed for intermittent infusion of fluids into the hollow fluid delivery tube in a synchronous manner when the heart is in diastole, and means for monitoring retroperfusion flow rate and blood pressure consisting of an electromagnetic flowmeter probe and a pressure transducer operatively attached to said fluid delivery tube and disposed for constant fluid pressure measurement, and automatic feedback means for termination or reduction of pump flow when said pressure means indicates internal pressure parameters have been exceeded.
Claim 13
Dependent Claim
78 words
The catheter claimed in Claim 9 wherein said means to administer fluids through said catheter in a synchronous pulsatile manner consists of a gravity-feed infusion container which is operatively attached to said hollow fluid catheter delivery tube to allow for direct and controlled infusion of a predetermined quantity of pharmacologic agent per unit time into said hollow fluid delivery tube, and an electromagnetic flowmeter probe and pressure transducer for constant measurement of retroperfusion flow rate and blood pressure.
Claim 14
Independent Claim
96 words
A method of medical treatment of the myocardium comprising: inserting a hollow catheter through the coronary sinus orifice; inflating a balloon catheter material sealed and secured about the distal extension of said catheter body, said balloon when inflated having a generally broadened base and a narrow tapered apex so as to seal said material against the vein interfacing with the coronary sinus orifice yet prevent excessive pressure build up in the coronary sinus; and infusing a pharmacologic fluid through the hollow fluid delivery tube for ultimate delivery to the pathological or diagnostic site in the myocardium.
Claim 15
Independent Claim
96 words
A method of medical treatment of the myocardium comprising: inserting a hollow catheter through the coronary sinus orifice; inflating a balloon catheter material sealed and secured about the distal extension of said catheter body, said balloon when inflated having a generally broadened base and a narrow tapered apex so as to seal said material against the vein interfacing with the coronary sinus orifice yet prevent excessive pressure build up in the coronary sinus; and infusing a pharmacologic fluid through the hollow fluid delivery tube for ultimate delivery to the pathological or diagnostic site in the myocardium.
Claim 16
Dependent Claim
32 words
-14. The use of a catheter apparatus in accordance with any one of Claims 1 to 12 for retroinfusion of fluids into the coronary sinus for treatment or diagnosis of the myocardium.
Claim 17
Dependent Claim
100 words
The use of an apparatus for medical treatment of the myocardium, which comprises inserting a hollow catheter through the coronary sinus orifice; inflating a balloon catheter material sealed and secured about the distal extension of said catheter body, said balloon when inflated having a generally broadened base and a narrow tapered apex so as to seal said material against the vein interfacing with the coronary sinus orifice yet prevent excessive pressure build up in the coronary sinus; and infusing a pharmacologic fluid through the hollow fluid delivery tube for ultimate delivery to the pathological or diagnostic site in the myocardium.
Claim 18
Dependent Claim
100 words
The use of an apparatus for medical treatment of the myocardium, which comprises inserting a hollow catheter through the coronary sinus orifice; inflating a balloon catheter material sealed and secured about the distal extension of said catheter body, said balloon when inflated having a generally broadened base and a narrow tapered apex so as to seal said material against the vein interfacing with the coronary sinus orifice yet prevent excessive pressure build up in the coronary sinus; and infusing a pharmacologic fluid through the hollow fluid delivery tube for ultimate delivery to the pathological or diagnostic site in the myocardium.
References Cited (Backward Citations)
No citation records indexed.
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