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EP0149693A1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Method of forming an antithrombogenic layer on medical devices

Assignee: Draeger Nederland Bv Te Best
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Filing: 1984-01-20
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Granted: —
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Expires: 2004-01-20
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Abstract

Abstract An antithrombogenic layer is formed on medical devices by preparing an aqueous solution of a photosensitive polymer, a cross-linking salt and heparin; coating the medical device with said solution; exposing the coated device to ultraviolet radiation.

Inventors

  • 👤 Martinus Henricus Kuypers

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 18:05
CPC Classifications
A; A61; A61L; A61L33/00; A61L33/0005; A61L33/0011; A61L33/0029

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 49 words
Method of forming on medical devices an antithrombogenic layer comprising polyvinyl alcohol and heparin, characterized by the steps of: a) preparing an aqueous solution of a photosensitive polymer, a cross-linking salt and heparin; b) coating the medical device with said solution; c) exposing the coated device to ultraviolet radiation.
Claim 2
Dependent Claim 49 words
Method of forming on medical devices an antithrombogenic layer comprising polyvinyl alcohol and heparin, characterized by the steps of: a) preparing an aqueous solution of a photosensitive polymer, a cross-linking salt and heparin; b) coating the medical device with said solution; c) exposing the coated device to ultraviolet radiation.
Claim 3
Dependent Claim 28 words
Method according to claim 1, characterized in that the antithrombogenic layer is crosslinked to such an extent that large biological molecules cannot penetrate the interior of the sensor.
Claim 4
Dependent Claim 37 words
Method according to claim 1 or 2 of forming an antithrombogenic layer on a polymeric surface, characterized in that before coating the surface with said solution, this surface is chemically hydrophylised by chemical etching in chromic-sulphuric acid.
Claim 5
Dependent Claim 28 words
Applying the method of claims 1, 2 or 3 for coating a chemical or physical sensor such as a pressure, pH or oxygen sensor with an antithrombogenic layer.
Claim 6
Dependent Claim 17 words
Applying the method of claims 1, 2 or 3 for coating a catheter with an antithrombogenic layer.
Claim 7
Dependent Claim 18 words
Applying the method of claims 1, 2 or 3 for coating a medical instrument with an antithrombogenic layer.
Claim 8
Dependent Claim 21 words
A medical device at least partially coated with an antithrombogenic layer by performing the method of claims 1, 2 or 3.

References Cited (Backward Citations)

US3677800A Cited
FR2142277A5 Cited

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