§
Luxuse
Patent Intelligence
Sign In
← Back to Patent Explorer
EP0132979A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Aqueous atelocollagen solution and method of preparing same

Assignee: Koken Co Ltd
•
Filing: 1984-07-10
•
Granted: —
•
Expires: 2004-07-10
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract An aqueous atelocollagen solution, which can be injected into living bodies as a medical material, has a pH value in the range from about 6.5 to about 8.0 and an osmolality in the range from about 250 to about 320 mOsm/KgH 2 0. The solution conveniently contains a phosphate buffer solution, or glucose and a phosphate buffersolution, as an agentto adjust the pH and osmolality within the ranges specified above. This aqueous atelocollagen solution can be prepared by dissolving atelocollagen in an aqueous acidic solution and adding one or more pH- and osmolality-adjusting agents to the resulting solution in such an amount as to adjust the pH and osmolality of the final solution to within the ranges mentioned above.

Inventors

  • 👤 Teruo Miyata
  • 👤 Toshio Taira

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 13:56
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/78

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 30 words
An aqueous atelocollagen solution having a pH value ranging from about 6.5 to about 8.0 and an osmolality in the range from about 250 to about 320 mOsm/KgH 2 0.
Claim 2
Dependent Claim 30 words
An aqueous atelocollagen solution having a pH value ranging from about 6.5 to about 8.0 and an osmolality in the range from about 250 to about 320 mOsm/KgH 2 0.
Claim 3
Dependent Claim 53 words
An aqueous atelocollagen solution as defined in claim 1 containing, as pH- and osmolality-adjusting agent, a phosphate buffer solution selected from combinations of KH 2 PO 4 with K 2 HPO 4 , KH 2 P0 4 with Na 2 HP0 4 and NaH 2 PO 4 with Na 2 HP0 4 .
Claim 4
Dependent Claim 57 words
An aqueous atelocollagen solution as defined in claim 1 containing, as pH- and osmolality-adjusting agents, glucose together with a phosphate buffer solution selected from combinations of KH 2 PO 4 with K 2 HPO 4 , KH 2 P0 4 with Na 2 HPO 4 and NaH 2 PO 4 with Na 2 H P0 4 .
Claim 5
Independent Claim 60 words
A method of preparing an aqueous atelocollagen solution, which comprises dissolving atelocollagen in an aqueous acidic solution and adding to the resulting solution one or more pH-and osmolality-adjusting agents in such an amount as to give a pH value in the range from about 6.5 to about 8.0 and an osmolality from about 250 to about 320 mOsm/KgH 2 0.
Claim 6
Independent Claim 60 words
A method of preparing an aqueous atelocollagen solution, which comprises dissolving atelocollagen in an aqueous acidic solution and adding to the resulting solution one or more pH-and osmolality-adjusting agents in such an amount as to give a pH value in the range from about 6.5 to about 8.0 and an osmolality from about 250 to about 320 mOsm/KgH 2 0.
Claim 7
Dependent Claim 59 words
A method of preparing an aqueous atelocollagen solution as defined in claim 4 wherein said pH- and osmolality adjusting agent is a phosphate buffer solution selected from combinations of KH 2 PO 4 with K 2 HPO 4 , KH 2 P0 4 with Na 2 HP0 4 and NaH 2 P0 4 with Na 2 HP0 4 .
Claim 8
Dependent Claim 60 words
A method of preparing an aqueous atelocollagen solution as defined in claim 4 wherein said pH- and osmolality-adjusting agents comprise glucose together with a phosphate buffer selected from combinations of KH 2 P0 4 with R 2 HPO 4 , KH 2 PO 4 with Na 2 HPO 4 and NaH 2 P0 4 with Na 2 HPO 4 .

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Maintenance schedule is calculated for granted US utility patents.

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag