EP0099508A2
Expired / Lapsed
EP
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Artificial pancreas
Assignee: Astellas Pharma Inc
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Filing: 1983-07-05
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Granted: —
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Expires: 2003-07-05
Abstract
Abstract An artificial pancreas comprising a blood sugar determination unit for measuring the blood sugar of the living body, an injection unit including a container for a blood sugar control agent and a feed pump for the control agent and adapted to inject the control agent into the living body, and an arithmetic control unit for calculating the dose of the control agent based on the blood sugar measurement and controlling the pump of the injection unit in accordance with the result of calculation. The blood sugar determination unit has an electrode assembly to be inserted into the living body for measuring the blood sugar. The feed pump comprises a plurality of rollers rotatably mounted on a rotatable roller holder along the outer periphery of the holder and an elastic tube having an intermediate portion reeved around some of the rollers under tension.
Inventors
- 👤 Hiroshi Prof. Abe
- 👤 Motoaki Prof. Shichiri
- 👤 Ryuzo Prof. Kawamori
- 👤 Tasuku Ichoh
- 👤 Kenji Iwatani
- 👤 Mamoru Higuchi
- 👤 Kiyotaka Takagi
- 👤 Norihiko Okamoto
- 👤 Toshiyuki Okudaira
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 20:11
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/168; A61M5/172; A61M5/1723
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
155 words
An artificial pancreas comprising a blood sugar determination unit for measuring the blood sugar of the living body, an injection unit including a container for a blood sugar control agent and a feed pump for the control agent and adapted to inject the control agent into the living body, and an arithmetic control unit for calculating the dose of the control agent based on the blood sugar measurement and controlling the pump of the injection unit in accordance with the result of calculation, the artificial pancreas being characterized in that the blood sugar determination unit has electrode means to be inserted into the living body for measuring the blood sugar, the feed pump comprising a plurality of rollers rotatably mounted on a rotatable roller holder along the outer periphery of the holder and an. elastic tube having an intermediate portion reeved around some of the rollers under tension, the arithmetic control unit having a microcomputer.
Claim 2
Dependent Claim
155 words
An artificial pancreas comprising a blood sugar determination unit for measuring the blood sugar of the living body, an injection unit including a container for a blood sugar control agent and a feed pump for the control agent and adapted to inject the control agent into the living body, and an arithmetic control unit for calculating the dose of the control agent based on the blood sugar measurement and controlling the pump of the injection unit in accordance with the result of calculation, the artificial pancreas being characterized in that the blood sugar determination unit has electrode means to be inserted into the living body for measuring the blood sugar, the feed pump comprising a plurality of rollers rotatably mounted on a rotatable roller holder along the outer periphery of the holder and an. elastic tube having an intermediate portion reeved around some of the rollers under tension, the arithmetic control unit having a microcomputer.
Claim 3
Dependent Claim
93 words
An artificial pancreas as defined in claim 1 wherein the injection unit comprises a container for a hypoglycemic agent, a container for a hyperglycemic agent, a feed pump for the hypoglycemic agent and a feed pump for the hyperglycemic agent and is adapted to inject the hypoglycemic agent or the hyperglycemic agent into the living body, and the arithmetic control unit calculates the doses of the hypoglycemic agent and the hyperglycemic agent based on the blood sugar measurement and controls the pumps of the injection unit in accordance with the result of calculation.
Claim 4
Dependent Claim
99 words
An artificial pancreas as defined in claim 1 or 2 wherein the blood sugar measuring electrode means comprises a bar-like anode insulated except at its front end serving as an electrode reaction portion and at its rear end serving as a lead wire connecting portion, and a cylindrical cathode having the anode fixedly provided therein, and the anode is cover over the surface of its front end with a hydrophilic semipermeable membrane permeable to hydrogen peroxide, then with an immobilized glucose oxidase membrane and further with a hydrophilic semipermeable membrane permeable to glucose, oxygen and hydrogen peroxide by lamination.
Claim 5
Dependent Claim
61 words
An artificial pancreas as defined in claim 3 wherein the cathode is formed on the outer surface of a cylinder, and the anode is inserted in the cylinder and provided with an insulator fixed at its front end to the front end of the cylinder, the anode and the cathode cylinder being fixed at their rear ends to a plastic plug.
Claim 6
Dependent Claim
52 words
An artificial pancreas as defined in claim 4 wherein the anode is a noble metal electrode insulated with glass or plastic except at its front end and rear end, and the cathode is a silver electrode or silver chloride electrode formed on the outer surface of a metal cylinder or plastic tube.
Claim 7
Dependent Claim
22 words
An artificial pancreas as defined in claim 3 wherein the hydrophilic semipermeable membrane permeable to hydrogen peroxide is a cellulose acetate film.
Claim 8
Dependent Claim
24 words
An artificial pancreas as defined in claim 3 wherein the hydrophilic semipermeable membrane permeable to glucose, oxygen and hydrogen peroxide is a polyurethane film.
Claim 9
Dependent Claim
118 words
An artificial pancreas as defined in claim 1 or 2 wherein the roller holder is formed with a plurality of circular bores parallel with the axis . of its rotation and equidistantly spaced apart on a circumference centered about the axis of rotation, the roller holder being formed in its outer peripheral side surface with a tube guide groove extending circumferentially thereof and partly positioned in the bores, the rollers being respectively fitted in the bores of the roller holder so as to be rotatable but substantially immovable radially and axially of the holder, the intermediate portion of the elastic tube being reeved around the portions of a predetermined number of the rollers positioned in the guide groove.
Claim 10
Dependent Claim
51 words
An artificial pancreas as defined in claim 8 wherein the circular bores extend through the roller holder in the direction of axis of its rotation, and the roller holder is provided on each of its axially opposite end surfaces with a roller retainer for preventing the axial movement of the rollers.
Claim 11
Dependent Claim
46 words
An artificial pancreas as defined in claim 9 wherein the roller holder is in the form of a short solid cylinder, and the tube guide groove is annular and is formed in the outer peripheral side surface of the roller holder over the entire circumference thereof.
Claim 12
Dependent Claim
19 words
An artificial pancreas as defined in claim 10 wherein the tube guide groove is substantially semicircular in cross section.
Claim 13
Dependent Claim
24 words
An artificial pancreas as defined in claim 10 wherein the roller retainer is in the form of a disk concentric with the roller holder.
Claim 14
Dependent Claim
24 words
An artificial pancreas as defined in claim 8 wherein the roller holder is made of polytetrafluoroethylene, and the rollers are made of stainless steel.
References Cited (Backward Citations)
No citation records indexed.
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