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EP0089232A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Perfluorocarbon liquids useful in eye treatment and diagnostic procedures

Assignee: Cincinnati Children's Hospital Medical Center
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Filing: 1983-03-15
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Granted: —
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Expires: 2003-03-15
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Abstract

Abstract Perfluorocarbon liquids are disclosed as being useful as substitutes for the vitreous or aqueous of the eye, and as transparentizing agents in the cornea or lens of the eye. Radiopaque liquid perfluorocarbons are useful as radiopaque agents in diagnostic procedures on the eye.

Inventors

  • 👤 Leland C. Clark, Jr.

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 18:21
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/02; A61K31/025; A61L; A61L27/00; A61L2430/00; A61L2430/16

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 16 words
An artificial vitreous or aqueous composition for an eye, comprising a perfluorocarbon or substituted derivative thereof.
Claim 2
Dependent Claim 16 words
An artificial vitreous or aqueous composition for an eye, comprising a perfluorocarbon or substituted derivative thereof.
Claim 3
Dependent Claim 32 words
A composition according to Claim 1, wherein said perfluorocarbon or substituted derivative thereof is in a physical state selected from a neat liquid, an emulsion, a gel, a solution and a suspension.
Claim 4
Dependent Claim 15 words
A composition according to Claim 1 or Claim 2, wherein said liquid is a perfluorocyclocarbon.
Claim 5
Dependent Claim 30 words
A composition according to Claim 3, wherein said perfluorocyclocarbon is selected from perfluoro-(methylcyclohexane), perfluoro(1,3-dimethylcyclohexane), perfluoro(decahydronaphthalene), perfluoro(decahydro-1-methylnapthalene), perfluoro(decahydrodimetbylnaphthalene), perfluorodimethyladamantane, perfluorotrimethylbicyclo [3.3.1] nonane, perfluorotetrahydrodicyclopentadiene, perfluorobicyclo[5.3.0]decane and perfluorodimethyl- bicyclo[3.3.1.] nonane, and mixtures thereof.
Claim 6
Dependent Claim 20 words
A radiopaque agent for use in diagnostic procedures on the eye, comprising a radiopaque liquid perfluorocarbon or substituted derivative thereof.
Claim 7
Dependent Claim 20 words
A radiopaque agent for use in diagnostic procedures on the eye, comprising a radiopaque liquid perfluorocarbon or substituted derivative thereof.
Claim 8
Dependent Claim 17 words
A radiopaque agent according to Claim 5, wherein said substituted derivative is a brominated or iodinated perfluorocarbon.
Claim 9
Dependent Claim 13 words
A radiopaque agent according to Claim 6, wherein said substituted derivative is perfluorooctylbromide.
Claim 10
Dependent Claim 23 words
A transparentizing agent for forming a transparent window in the cornea or lens of an eye, comprising a perfluorocarbon or substituted derivative thereof.
Claim 11
Dependent Claim 23 words
A transparentizing agent for forming a transparent window in the cornea or lens of an eye, comprising a perfluorocarbon or substituted derivative thereof.
Claim 12
Dependent Claim 23 words
A transparentizing agent according to Claim 8, wherein said perfluorocarbon or substituted derivative thereof is as defined in any one of Claims 2-4.

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