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EP0063014A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

A method of preparing coated solid preparations

Assignee: Sankyo Co Ltd
•
Filing: 1982-04-01
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Granted: —
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Expires: 2002-04-01
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Abstract

Abstract Solid materials, especially pharmaceutical preparations, are coated, without the use of solvents, with a powdered film-forming polymer and with a liquid plasticizer having an affinity for the polymer.

Inventors

  • 👤 Yoshihiko C/O Product Development Lab. Ikegami
  • 👤 Kozo C/O Product Development Lab. Kurihara
  • 👤 Izuo C/O Product Development Lab. Ichikawa
  • 👤 Hisanori C/O Product Development Lab. Nakane

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 13:37
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/50; A61K9/5073; A61K9/20; A61K9/28; A61K9/2806; A61K9/2833; A61K9/284; A61K9/286; A61K9/2866; A61K9/2886; A61K9/282

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 33 words
A method of coating a solid material with a polymer, characterised in that said material is coated with a powdered film-forming polymer and with a liquid plasticizer having an affinity for said polymer.
Claim 2
Independent Claim 33 words
A method of coating a solid material with a polymer, characterised in that said material is coated with a powdered film-forming polymer and with a liquid plasticizer having an affinity for said polymer.
Claim 3
Dependent Claim 23 words
A method as claimed in claim 1, in which said material is first coated with said plasticizer and then with said powdered polymer.
Claim 4
Dependent Claim 91 words
A method as claimed in claim 1, in which said polymer is one or more of hydroxypropyl methylcellulose phthalate, cellulose acetate phthalate, methyl methacrylate/methacrylic acid copolymer, polyvinyl acetate phthalate, carboxymethyl ethylcellulose, polyvinyl alcohol phthalate, starch acetate phthalate, cellulose acetate succinate, styrene/maleic acid copolymer, polyvinyl acetal diethylaminoacetate, poly(dimethylaminoethyl methacrylate), benzylaminomethylcellulose, diethylaminomethylcellulose, benzylaminoethyl hydroxyethylcellulose, cellulose acetate diethylaminoacetate, cellulose acetate dibutylaminohydroxypropyl ether, sodium carboxymethylcellulose, methylcellulose, hydroxyethylcellulose, polyvinyl alcohol, gelatin, polyvinylpyrrolidone, pyrrolidone/vinyl acetate copolymer, polyethylene glycol, hydroxypropyl methylcellulose, hydroxypropylcellulose, vinylpyrrolidone/vinyl acetate copolymer, ethylcellulose, methylyinylpyridine/ methyl acrylate methacrylate copolymer, acetyl cellulose, nitrocellulose, polyvinyl acetate and shellac.
Claim 5
Dependent Claim 36 words
A method as claimed in claim 3, in which said polymer is one or more of hydroxypropyl methylcellulose phthalate, carboxymethyl ethylcellulose, polyvinyl acetal diethylaminoacetate, vinylpyrrolidone/ vinyl acetate copolymer, ethylcellulose and mixtures of two or more thereof.
Claim 6
Independent Claim 24 words
A method as claimed in any one of the preceding claims, in which the powdered polymer has a particle size less than 100 pm.
Claim 7
Dependent Claim 20 words
A method as claimed in claim 5, in which the powdered polymer has a particle size less than 30 µm.
Claim 8
Dependent Claim 20 words
A method as claimed in claim 6, in which the powdered polymer has a particle size less than 10 µm.
Claim 9
Independent Claim 46 words
A method as claimed in any one of the preceding claims, in which the plasticizer is one or more of triacetin, glycerol monocaprylate, monoalkyl esters of diacetin, dibutyl phthalate, glycerol, diacetone alcohol, propylene glycol, polyethylene glycol 400, polyethylene glycol 4000, polyoxyethylene sorbitan monooleate and sorbitan trioleate.
Claim 10
Dependent Claim 35 words
A method as claimed in claim 8, in which said plasticizer is one or more of triacetin, glycerol monocaprylate, propylene glycol, polyethylene glycol 4000, polyoxyethylene sorbitan monooleate, monoalkyl esters of diacetin and polyethylene glycol 400.
Claim 11
Independent Claim 41 words
A method as claimed in any one of the preceding claims, in which the plasticizer is solid at ambient temperature and is melted prior to or after its application to said solid material but prior to coating with said powdered polymer.
Claim 12
Independent Claim 20 words
A method as claimed in any one of the preceding claims, in which said solid material is a pharmaceutical preparation.
Claim 13
Dependent Claim 23 words
A method as claimed in claim 11, in which said preparation is in the form of granules, fine powders, pills, capsules or tablets.

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