EP0044624B1
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Lyophilized hydrocolloid foam
Assignee: ER Squibb and Sons LLC
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Filing: 1981-06-23
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Granted: 1984-10-31
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Expires: 2001-06-23
Abstract
Abstract A lyophilized foam sponge product having medically useful hemostatic and adhesive properties formed from the hydrocolloids, gelatin, pectin, and sodium carboxymethylcellulose and having a density of from about 0.01 to about 0.10 grams/cc. The gelatin is present at from about 20% to about 80% by weight of the final product and the pectin and sodium carboxymethylcellulose are each present at from about 10% to about 50% by weight of the final product. The product is prepared by forming an aqueous colloidal dispersion of hydrocolloids, aerating or foaming, freezing, and lyophilizing.
Inventors
- 👤 John M. Pawelchak
- 👤 Yu-Chang J. Wang
- 👤 Anthony L. Lavia
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 15:51
CPC Classifications
A; A61; A61L; A61L24/00; A61L24/001; A61L24/0036; A61L15/00; A61L15/16; A61L15/42; A61L15/60; A61L24/04; A61L24/043; A61L2400/00; A61L2400/04
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
37 words
A medically useful lyophilised sponge product having a density of 0.01 to 0.10 g/cm 3 , characterized in that the sponge product comprises a mixture of the hydrocolloids, gelatin, pectin and sodium carboxymethylcellulose, in the following amounts:-
Claim 2
Dependent Claim
37 words
A medically useful lyophilised sponge product having a density of 0.01 to 0.10 g/cm 3 , characterized in that the sponge product comprises a mixture of the hydrocolloids, gelatin, pectin and sodium carboxymethylcellulose, in the following amounts:-
Claim 3
Dependent Claim
38 words
A product according to claim 1 wherein said pectin and sodium carboxymethylcellulose are each present in an amount from 15% to 35% by weight and said gelatin is present in an amount from 30% to 70% by weight.
Claim 4
Dependent Claim
21 words
A product according to claim 2 wherein said gelatin, pectin, and sodium carboxymethylcellulose are present in the same amount by weight.
Claim 5
Dependent Claim
14 words
A product according to claim 3 having a density of 0.04 g/cm 3 .
Claim 6
Dependent Claim
34 words
A product according to claim 2 wherein said gelatin is present in an amount of 50% by weight and said pectin and sodium carboxymethylcellulose are each present in an amount of 25% by weight.
Claim 7
Dependent Claim
14 words
A product according to claim 5 having a density of 0.02 g/cm 3 .
Claim 8
Dependent Claim
14 words
A product according to claim 5 having a density of 0.03 g/cm 3 .
Claim 9
Dependent Claim
34 words
A product according to claim 2 wherein said gelatin is present in an amount of 60% by weight and said pectin and sodium carboxymethylcellulose are each present in an amount of 20% by weight.
Claim 10
Dependent Claim
17 words
A product according to any preceding claim wherein a pharmaceutically active material is included within the sponge.
Claim 11
Dependent Claim
13 words
A product according to claim 9 wherein the pharmaceutically active material is thrombin.
Claim 12
Independent Claim
69 words
A method of preparing a product according to any preceding claim, comprising adding a dry blend comprising a mixture of the hydrocolloids in the stated proportions, to water with agitation to form a colloidal dispersion, said dispersion having a solids content of from 1% to 20% by weight, aerating or foaming the colloidal dispersion so that its volume increases by 10% to 600%, and freezing and lyophilizing the dispersion.
References Cited (Backward Citations)
US3339546A
Cited
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